The site of the ancient city of Gomfoi (pronounced Gomfi) is located 2 km northwest of Episkopi within the region of Mouzaki. The ruins of Gomfoi include a fortified wall, part of which was recently excavated.
In 48 B.C., Gomfoi initially took the side of Pompey following the policy of the Commons of Thessaly. The Gomfians refused to open their gates to the army of Caesar, and after a lengthy siege Caesar overtook the city. In the sixth century AD during the reign of Justinian, the fortifications of the city were strengthened and during the Byzantine era it became the seat of a Bishopric.